Enfermedad de Chagas en el sistema nervioso central en paciente con infección por VIH: dificultades diagnósticas y terapéutica

Federico Simioli, Milagro Sánchez-Cunto, Elsa Velázquez, Susana Lloveras, Tomás Orduna


Chagas disease (ChD), caused by the protozoan Trypanosoma cruzi, is an endemic anthropozoonosis in Latin America, linked to deficientssocio-economic and cultural aspects and is considered one of the neglected tropical diseases. We report a fatal case of Chagas disease reactivation with central nervous system involvement in a patient with HIV infection, whose diagnosis was confirmedby positive PCR (polymerase chain reaction) test of blood, with treatment response efficien with benznidazol and management and etiologic treatment was difficuldue to limited number of antitrypanosomal drugs and the occurrence of frequent and serious adverse effects

Palabras clave

Chagas; reactivación; VIH; RPC

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