Vol. 40 No. 5 (2023): Octubre
Clinical Case

Use of ceftazidime-avibactam in a preterm infant with urinary tract infection with bacteremia caused by carbapenemase-producing Klebsiella pneumoniae

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  • Miguel Angel Pantoja Herrera,
  • Luis Delpiano,
  • Tamara Arriagada
Miguel Angel Pantoja Herrera
Hospital Dr. Luis Tisné Brousse Clínica Alemana
Bio
Luis Delpiano
Servicio de Pediatría, Hospital Clínico San Borja Arriarán Facultad de Medicina Universidad de Chile
Tamara Arriagada
Unidad de Neonatología. Hospital Clínico San Borja Arriarán. Servicio de Neonatología. Clínica Alemana

Published 2023-10-12

Keywords

How to Cite

1.
Pantoja Herrera MA, Delpiano L, Arriagada T. Use of ceftazidime-avibactam in a preterm infant with urinary tract infection with bacteremia caused by carbapenemase-producing Klebsiella pneumoniae. Rev. Chilena. Infectol. [Internet]. 2023 Oct. 12 [cited 2026 Jan. 16];40(5). Available from: https://www.revinf.cl/index.php/revinf/article/view/1748

Copyright (c) 2023 Miguel Angel Pantoja Herrera, Luis Delpiano, Tamara Arriagada

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Neonates are high risk patients regarding morbimortality se-condary to infections during their neonatal intensive care unit stay, which is associated to a progressive increase in the report of multidrug resistant organism infections, that require the use of new antimicrobial. We report the case of a 36-week preterm with an urinary tract infection with bacteriemia caused by carbapenemase-producing Klebsiella pneumoniae treated effectively with 14 day of ceftazidime-avibactam, without observed adverse effects. To our knowledge, this is the first case report in our country of the use of this antibiotic in neonatal population. More information is needed regarding efficacy and safety of ceftazidime-avibactam in this group of patients.
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