Seroprevalence and positiveness of infectious agents in a blood bank in Barranquilla, norther of Colombia
Published 2025-08-23
How to Cite
Copyright (c) 2025 Johan Bula-Viecco, Hernán Argote-Berdugo, Ricardo Ávila de la Hoz, Juan Diego Altamiranda-Vargas, Soraya Salcedo-Mendoza, Daniel Suarez-Posada, Ronald Maestre-Serrano

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Background: Blood transfusions are life-saving; yet, despite measures like surveys and immunoassays, there remains a risk of transmitting infectious agents. Aim: To determine the seroprevalence and positivity of infectious markers in repeat volunteer donors at a blood bank in the Department of Atlántico between 2017 and 2023. Methods: Descriptive, cross-sectional study that included blood donors who met the current technical guidelines of the National Institute of Health for the selection of blood donors in Colombia. Sociodemographic variables and those associated with the seroprevalence of transfusion-transmissible infections and serological marker positivity were analyzed. Results: A total of 297,547 donors were received, of whom 64.2% were men and 35.8% were women; 61.8% were between the ages of 20 and 39. The cumulative reactivity rate per 100 donors was 3.76 (HBsAg: 0.11, HIV: 0.22, Core: 1.39, T. cruzi: 0.6, HTLV: 0.19, T. pallidum: 1.90, HCV: 0.22) and the cumulative positivity rate was 0.22 per 100 donations (HIV: 0.09, HB: 0.07, Chagas: 0.02, HTLV: 0.04, HCV: 0.01). Conclusion: A significant seroprevalence rate of infectious markers and positivity was found, with a predominance of syphilis, HIV, and hepatitis B.
