Vol. 38 No. 2 (2021): Abril
Laboratory and Infectious Diseases

Characterization of multiresistant gram-negative bacilli, isolated in patients hospitalized in health institutions in Barranquilla (Colombia)

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  • Marlene Guerra Sarmiento,
  • Fernando Ruíz-Martin Leyes,
  • Laura Arzuza-Ortega,
  • Ronald Maestre Serrano
Marlene Guerra Sarmiento
Laboratorio de Salud Pública del Atlántico, Secretaría de Salud del Atlántico, Barranquilla, Colombia.
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Fernando Ruíz-Martin Leyes
Laboratorio de Salud Pública del Atlántico, Secretaría de Salud del Atlántico, Barranquilla, Colombia.
Bio
Laura Arzuza-Ortega
Laboratorio de Salud Pública del Atlántico, Secretaría de Salud del Atlántico, Barranquilla, Colombia.
Bio
Ronald Maestre Serrano
Universidad Simón Bolívar. Facultad de Ciencias de la Salud. Barranquilla, Colombia
Bio

Published 2021-05-14

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How to Cite

1.
Guerra Sarmiento M, Ruíz-Martin Leyes F, Arzuza-Ortega L, Maestre Serrano R. Characterization of multiresistant gram-negative bacilli, isolated in patients hospitalized in health institutions in Barranquilla (Colombia). Rev. Chilena. Infectol. [Internet]. 2021 May 14 [cited 2025 Nov. 4];38(2). Available from: https://www.revinf.cl/index.php/revinf/article/view/655

Copyright (c) 2021 Marlene Guerra Sarmiento, Fernando Ruíz-Martin Leyes, Laura Arzuza-Ortega, Ronald Maestre Serrano

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Abstract

Background: The emergence of carbapenem resistant enterobacteria has become a problem of public health worldwide, because it is associated with high mortality rates, increased levels of resistance to other antimicrobials, increased potential for dissemination transition and increase in health care costs. Aim: To characterize multiresistant gram-negative bacilli, isolated in patients hospitalized in health institutions of Barranquilla (Colombia). Methods: A descriptive study was conducted on the phenotypic and genotypic characterization of bacterial resistance in infections associated with health care, mediated by carbapenemases in bacterial isolates sent by laboratories belonging to the laboratory network of the department of Atlántico. Results: KPC was the most frequent carbapenemase in Enterobacterales (27.6%), predominantly in Klebsiella pneumoniae (13.1%) alone and associated with other carbapenemases. In Pseudomonas aeruginosa, VIM carbapenemase (32.8%) predominated and OXA in Acinetobacter baumannii (17.1%). Conclusion: A wide distribution of multi-resistant strains producing carbapenemases in Atlantic health institutions was found, which expressed the following resistance mechanisms: KPC, VIM, NDM, OXA
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