Vol. 35 No. 3 (2018): June
Clinical Case

Post-surgical ventriculitis due to extensively resistant Pseudomonas aeruginosa treated with intrathecal colistin. Pediatric case report and literature review

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  • Jasmín Abad-Restrepo,
  • Alejandro Díaz-Díaz,
  • Natalia Osorio-Cadavid

Published 2018-07-16

Keywords

How to Cite

1.
Abad-Restrepo J, Díaz-Díaz A, Osorio-Cadavid N. Post-surgical ventriculitis due to extensively resistant Pseudomonas aeruginosa treated with intrathecal colistin. Pediatric case report and literature review. Rev. Chilena. Infectol. [Internet]. 2018 Jul. 16 [cited 2025 Nov. 21];35(3). Available from: https://www.revinf.cl/index.php/revinf/article/view/125

Copyright (c) 2018 Jasmín Abad-Restrepo, Alejandro Díaz-Díaz, Natalia Osorio-Cadavid

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Abstract

Use of Intrathecal colistin has increased in recent years and has become an alternative for the management of infections of the central nervous system caused by multidrug resistant (MDR) bacteria. Evidence of therapeutic success and safety profile is increasing, particularly in MDR Acinetobacter baumanii infections in adults. Conversely, evidence in children is limited. We present a case of an 11-year-old female with postsurgical meningitis caused by an extensively resistant Pseudomonas aeruginosa strain and treated with venous and intrathecal colistin. The evidence of its use in children with nosocomial meningitis by MDR Gram negative bacteria is reviewed.
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